Biochemical Engineering
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By James M. Lee, Professor, Washington State University

To go to the newly updated web site, click here. 

This book was originally published by Prentice Hall in 1992. It was converted to an ebook (pdf format) in 2001 and updated in 2005.

Click here for the ordering information.

Some important features of the book include:

Many solved examples and chapter-end problems for home works.
Clear explanation for enzyme and cell kinetics and bioreactor design.
Whole book in one pdf file for easy searching, browsing, reading, and printing. 
Inclusion of laboratory experiments.
Being updated frequently. 

 To instructors:

Most instructors prepare their own notes to cover the topics of their interests. Students frequently are required to buy an expensive textbook for several chapters that instructors cover.
This ebook covers main topics of biochemical engineering that most instructors teach in the class. 
Adopting this ebook as your textbook not only help you to teach the course effectively, but also help students to save monies. Students in your class will get 50% discount from the price of the regular printable version.
Please write to the author (bcheg at jmlee.mailc.net) if you are interested in adopting this ebook for your class. 

 If you want to see how the ebook looks like, download the sample (right-button click and choose 'save target as') and view the downloaded file by using Acrobat Reader, which can be obtained free from www.adobe.com.

The outline of the book is as follows.

Chapter 1    Introduction

Chapter 2    Enzyme Kinetics

Simple enzyme kinetics, bioreactor design, inhibition, and other influences

Chapter 3    Immobilized Enzyme

Immobilization techniques and  effect of mass transfer resistance

Chapter 4    Industrial Applications of Enzymes

Carbohydrates, starch conversion, and cellulose conversion

Chapter 5    Cell Cultivations

Microbial, animal, and plant cell cultivations, cell growth measurement, and cell immobilization

Chapter 6    Cell Kinetics and Fermenter Design

Growth cycle, cell kinetics, batch, continuous, and plug-flow stirred-tank fermenter, multiple fermenters in series, fermenter with cell recycling, alternative fermenters, and structured kinetic models

Chapter 7    Genetic Engineering

DNA and RNA, cloning of genes, stability of recombinant cells, and genetic engineering of plant cells

Chapter 8    Sterilization

Sterilization methods, thermal death kinetics, design criterion, batch and continuous sterilization, and air sterilization

Chapter 9    Agitation and Aeration

Basic mass-transfer concepts, mass-transfer coefficient, interfacial area, gas hold-up, power consumption, oxygen absorption rate,  scale-up, and  shear sensitive mixing

Chapter 10  Downstream Processing

Solid-liquid separation, cell rupture, recovery, and purification

 

Total 350 pages, formatted for easy viewing and printing.

Updated on 10/27/06.

 

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